3FVX

Human kynurenine aminotransferase I in complex with tris

3FVX の概要

• エントリーDOI: 10.2210/pdb3fvx/pdb
• 分子名称: Kynurenine--oxoglutarate transaminase 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: alpha beta protein plp dependent protein aminotransferase lyase pyridoxal phosphate transferase, alternative splicing, aminotransferase, cytoplasm, lyase, pyridoxal phosphate, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: Q16773
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96480.12

構造登録者

Han, Q.,Robinson, H.,Cai, T.,Tagle, D.A.,Li, J. (登録日: 2009-01-16, 公開日: 2009-05-19, 最終更新日: 2023-11-22)

• 主引用文献: Han, Q.,Robinson, H.,Cai, T.,Tagle, D.A.,Li, J.; Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K; J.Med.Chem., 52:2786-2793, 2009; PubMed: 19338303; DOI: 10.1021/jm9000874

実験手法

X-RAY DIFFRACTION (1.5 Å)