3FVL

Crystallogic studies on the Complex of Carboxypeptidase A with inhibitors using alpha-hydroxy ketone as zinc-binding group

3FVL の概要

• エントリーDOI: 10.2210/pdb3fvl/pdb
• 分子名称: Carboxypeptidase A1, ZINC ION, (2R)-2-benzyl-5-hydroxy-4-oxopentanoic acid, ... (4 entities in total)
• 機能のキーワード: carboxypeptidase a, alpha-hydroxy ketone, inhibitor, carboxypeptidase, hydrolase, metal-binding, metalloprotease, polymorphism, protease, secreted, zinc, zymogen
• 由来する生物種: Bos taurus (Bovine)
• 細胞内の位置: Secreted, extracellular space: P00730
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 104373.30

構造登録者

Wang, S.F.,Jin, J.-Y.,Tian, G.R. (登録日: 2009-01-16, 公開日: 2010-01-12, 最終更新日: 2023-11-01)

• 主引用文献: Wang, S.F.,Jin, J.-Y.,Zeng, Z.H.,Tian, G.R.; Optical 2-benzyl-5-hydroxy4oxopentanoic acids against carboxypeptidase A: Synthesis, kinetic evaluation and X-ray crystallographic study; CHIN.CHEM.LETT., 21:159-162, 2010; DOI: 10.1016/j.cclet.2009.09.005

実験手法

X-RAY DIFFRACTION (1.85 Å)