3FV5

Crystal Structure of E. coli Topoisomerase IV co-complexed with inhibitor

3FV5 の概要

• エントリーDOI: 10.2210/pdb3fv5/pdb
• 分子名称: DNA topoisomerase 4 subunit B, 1-(4-acetyl-6-pyridin-3-yl-1H-benzimidazol-2-yl)-3-ethylurea (3 entities in total)
• 機能のキーワード: topoisomerase iv b subunit complex, antibiotic resistance, atp-binding, nucleotide-binding, topoisomerase, isomerase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45351.02

構造登録者

Wei, Y.,Charifson, P.,LeTiran, A. (登録日: 2009-01-15, 公開日: 2010-01-26, 最終更新日: 2023-09-06)

• 主引用文献: Wei, Y.,Letiran, A.; Design and syntheses of novel C7-derived-aminobenzimidazole ureas: bacterial gyrase/topoisomerase IV inhibitors with potent Gram-positve antibacterial activity; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)