3FUO
The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A
Summary for 3FUO
| Entry DOI | 10.2210/pdb3fuo/pdb |
| Descriptor | Botulinum neurotoxin type A (2 entities in total) |
| Functional Keywords | botulinum neurotoxin, ganglioside binding, hydrolase, membrane, metal-binding, metalloprotease, neurotoxin, pharmaceutical, protease, secreted, toxin, transmembrane, zinc |
| Biological source | Clostridium botulinum |
| Cellular location | Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: P10845 |
| Total number of polymer chains | 1 |
| Total formula weight | 49751.33 |
| Authors | Fu, Z.,Chen, C.,Barbieri, J.T.,Kim, J.-J.P.,Baldwin, M.R. (deposition date: 2009-01-14, release date: 2009-06-16, Last modification date: 2023-09-06) |
| Primary citation | Fu, Z.,Chen, C.,Barbieri, J.T.,Kim, J.J.,Baldwin, M.R. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F Biochemistry, 48:5631-5641, 2009 Cited by PubMed: 19476346DOI: 10.1021/bi9002138 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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