3FTG

Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza

Summary for 3FTG

• Entry DOI: 10.2210/pdb3ftg/pdb
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NP366-N3A variant peptide from influenza virus, ... (4 entities in total)
• Functional Keywords: h2db, mouse mhc, influenza, immunology, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, secreted, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• Total number of polymer chains: 3
• Total formula weight: 45419.93

Authors

Gras, S.,Guillonneau, C.,Rossjohn, J. (deposition date: 2009-01-12, release date: 2009-12-29, Last modification date: 2023-09-06)

• Primary citation: Valkenburg, S.A.,Gras, S.,Guillonneau, C.,La Gruta, N.L.,Thomas, P.G.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C.,Turner, S.J.,Kedzierska, K.; Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.; Plos Pathog., 6:e1001039-e1001039, 2010; PubMed: 20711359; DOI: 10.1371/journal.ppat.1001039

Experimental method

X-RAY DIFFRACTION (2.6 Å)