3FTG

Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza

3FTG の概要

• エントリーDOI: 10.2210/pdb3ftg/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NP366-N3A variant peptide from influenza virus, ... (4 entities in total)
• 機能のキーワード: h2db, mouse mhc, influenza, immunology, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, secreted, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45419.93

構造登録者

Gras, S.,Guillonneau, C.,Rossjohn, J. (登録日: 2009-01-12, 公開日: 2009-12-29, 最終更新日: 2023-09-06)

• 主引用文献: Valkenburg, S.A.,Gras, S.,Guillonneau, C.,La Gruta, N.L.,Thomas, P.G.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C.,Turner, S.J.,Kedzierska, K.; Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.; Plos Pathog., 6:e1001039-e1001039, 2010; PubMed: 20711359; DOI: 10.1371/journal.ppat.1001039

実験手法

X-RAY DIFFRACTION (2.6 Å)