3FSJ

Crystal structure of benzoylformate decarboxylase in complex with the inhibitor MBP

3FSJ の概要

• エントリーDOI: 10.2210/pdb3fsj/pdb
• 関連するPDBエントリー: 3D7K 3F6B
• 分子名称: Benzoylformate decarboxylase, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: thiamin adduct, aromatic hydrocarbons catabolism, calcium, decarboxylase, lyase, magnesium, mandelate pathway, metal binding, thiamine pyrophosphate, metal-binding
• 由来する生物種: Pseudomonas putida
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57068.27

構造登録者

Brandt, G.S.,Kenyon, G.L.,McLeish, M.J.,Jordan, F.,Petsko, G.A.,Ringe, D. (登録日: 2009-01-09, 公開日: 2009-01-27, 最終更新日: 2023-09-06)

• 主引用文献: Brandt, G.S.,Kneen, M.M.,Chakraborty, S.,Baykal, A.T.,Nemeria, N.,Yep, A.,Ruby, D.I.,Petsko, G.A.,Kenyon, G.L.,McLeish, M.J.,Jordan, F.,Ringe, D.; Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor.; Biochemistry, 48:3247-3257, 2009; PubMed: 19320438; DOI: 10.1021/bi801950k

実験手法

X-RAY DIFFRACTION (1.37 Å)