3FRK

X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine

3FRK の概要

• エントリーDOI: 10.2210/pdb3frk/pdb
• 分子名称: QdtB, (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total)
• 機能のキーワード: aminotransferase, sugar-modification, natural porduct, transferase
• 由来する生物種: Thermoanaerobacterium thermosaccharolyticum (Thermoanaerobacterium thermosaccharolyticum)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86916.36

構造登録者

Thoden, J.B.,Holden, H.M. (登録日: 2009-01-08, 公開日: 2009-02-17, 最終更新日: 2023-09-06)

• 主引用文献: Thoden, J.B.,Schaffer, C.,Messner, P.,Holden, H.M.; Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.; Biochemistry, 48:1553-1561, 2009; PubMed: 19178182; DOI: 10.1021/bi8022015

実験手法

X-RAY DIFFRACTION (2.15 Å)