3FPS

The Structure of Sarcoplasmic Reticulum Ca2+-ATPase Bound To Cyclopiazonic and ADP

Summary for 3FPS

Entry DOI	10.2210/pdb3fps/pdb
Descriptor	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, ... (5 entities in total)
Functional Keywords	calcium-transporting atpase sarcoplasmic reticulum, fast twitch skeletal muscle isoform, endoplasmic reticulum, hydrolase
Biological source	Oryctolagus cuniculus (Rabbit)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : P04191
Total number of polymer chains	1
Total formula weight	110414.77
Authors	Moncoq, K.,Morth, J.P.,Bublitz, M.,Laursen, M.,Nissen, P.,Young, H.S. (deposition date: 2009-01-06, release date: 2009-04-07, Last modification date: 2023-11-01)
Primary citation	Laursen, M.,Bublitz, M.,Moncoq, K.,Olesen, C.,Moller, J.V.,Young, H.S.,Nissen, P.,Morth, J.P. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J.Biol.Chem., 284:13513-13518, 2009 Cited by PubMed: 19289472 DOI: 10.1074/jbc.C900031200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation