3FPC

Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-294 of T. brockii ADH by E. histolytica ADH

3FPC の概要

• エントリーDOI: 10.2210/pdb3fpc/pdb
• 関連するPDBエントリー: 3FPL
• 分子名称: NADP-dependent alcohol dehydrogenase, ZINC ION, CACODYLATE ION, ... (9 entities in total)
• 機能のキーワード: oxydoreductase, bacterial alcohol dehydrogenase, domain exchange, chimera, metal-binding, nadp, oxidoreductase
• 由来する生物種: Thermoanaerobacter brockii (Thermoanaerobium brockii); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 154169.82

構造登録者

Felix, F.,Goihberg, E.,Shimon, L.,Burstein, Y. (登録日: 2009-01-05, 公開日: 2010-01-19, 最終更新日: 2023-11-01)

• 主引用文献: Goihberg, E.,Peretz, M.,Tel-Or, S.,Dym, O.,Shimon, L.,Frolow, F.,Burstein, Y.; Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms; Biochemistry, 49:1943-1953, 2010; PubMed: 20102159; DOI: 10.1021/bi901730x

実験手法

X-RAY DIFFRACTION (1.4 Å)