3FOE

Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

3FOE の概要

• エントリーDOI: 10.2210/pdb3foe/pdb
• 関連するPDBエントリー: 2NOV 3FOF
• 分子名称: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(P*AP*CP*CP*AP*AP*GP*GP*TP*CP*AP*TP*GP*AP*AP*T)-3'), ... (7 entities in total)
• 機能のキーワード: quinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, clinafloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna
• 由来する生物種: Streptococcus pneumoniae; 詳細
• 細胞内の位置: Cell membrane; Peripheral membrane protein (By similarity): P72525
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 195299.44

構造登録者

Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (登録日: 2008-12-30, 公開日: 2009-02-24, 最終更新日: 2023-11-01)

• 主引用文献: Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases; Nat.Struct.Mol.Biol., 16:667-669, 2009; PubMed: 19448616; DOI: 10.1038/nsmb.1604

実験手法

X-RAY DIFFRACTION (4.001 Å)