3FO7

Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site

Replaces:  2DV8Replaces:  1TI0

Summary for 3FO7

• Entry DOI: 10.2210/pdb3fo7/pdb
• Related: 1FB2
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, INDOMETHACIN, ... (4 entities in total)
• Functional Keywords: pla2, anti-inflammatory, anti-coagulant, indomethacin, hydrolase
• Biological source: Daboia russelli pulchella
• Total number of polymer chains: 1
• Total formula weight: 14371.81

Authors

Singh, N.,Prem Kumar, R.,Sharma, S.,Kaur, P.,Singh, T.P. (deposition date: 2008-12-29, release date: 2009-01-20, Last modification date: 2023-11-01)

• Primary citation: Singh, N.,Prem Kumar, R.,Sharma, S.,Kaur, P.,Singh, T.P.; Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)