3FN0

Crystal structure of HIV-1 neutralizing human Fab Z13e1 in complex with a 12-residue peptide containing the Z13e1 epitope on gp41

3FN0 の概要

• エントリーDOI: 10.2210/pdb3fn0/pdb
• 分子名称: Fab Z13e1, Envelope polyprotein gp160, ... (4 entities in total)
• 機能のキーワード: z13e1, z13, hiv, env, gp41, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49074.92

構造登録者

Pejchal, R.,Wilson, I.A.,Zwick, M.B. (登録日: 2008-12-22, 公開日: 2009-06-23, 最終更新日: 2023-09-06)

• 主引用文献: Pejchal, R.,Gach, J.S.,Brunel, F.M.,Cardoso, R.M.,Stanfield, R.L.,Dawson, P.E.,Burton, D.R.,Zwick, M.B.,Wilson, I.A.; A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.; J.Virol., 83:8451-8462, 2009; PubMed: 19515770; DOI: 10.1128/JVI.00685-09

実験手法

X-RAY DIFFRACTION (1.8 Å)