3FMO

Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19

3FMO の概要

• エントリーDOI: 10.2210/pdb3fmo/pdb
• 関連するPDBエントリー: 3FMP
• 分子名称: Nuclear pore complex protein Nup214, ATP-dependent RNA helicase DDX19B, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: nuclear porin, nuclear pore complex, nucleocytoplasmic transport, mrna export, protein interaction, helicase, beta-propeller, dead box, glycoprotein, mrna transport, nucleus, phosphoprotein, protein transport, proto-oncogene, translocation, transport, atp-binding, hydrolase, membrane, nucleotide-binding, rna-binding, protein transport-hydrolase complex, oncoprotein-hydrolase complex, oncoprotein/hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus, nuclear pore complex : P35658; Cytoplasm: Q9UMR2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 83888.94

構造登録者

Napetschnig, J.,Debler, E.W.,Blobel, G.,Hoelz, A. (登録日: 2008-12-22, 公開日: 2009-05-19, 最終更新日: 2023-09-06)

• 主引用文献: Napetschnig, J.,Kassube, S.A.,Debler, E.W.,Wong, R.W.,Blobel, G.,Hoelz, A.; Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19.; Proc.Natl.Acad.Sci.USA, 106:3089-3094, 2009; PubMed: 19208808; DOI: 10.1073/pnas.0813267106

実験手法

X-RAY DIFFRACTION (2.51 Å)