3FMG

Structure of rotavirus outer capsid protein VP7 trimer in complex with a neutralizing Fab

3FMG の概要

• エントリーDOI: 10.2210/pdb3fmg/pdb
• 分子名称: Fab of neutralizing antibody 4F8, light chain, Fab of neutralizing antibody 4F8, heavy chain, Glycoprotein VP7, ... (4 entities in total)
• 機能のキーワード: antibody-antigen complex, calcium dependent trimer, antiparallel beta-sandwich, jelly roll, alpha-beta-alpha sandwich, rossmann fold, capsid protein, endoplasmic reticulum, glycoprotein, membrane, transmembrane, virion, immune system
• 由来する生物種: Simian rotavirus; 詳細
• 細胞内の位置: Virion (By similarity): P12476
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 78281.81

構造登録者

Aoki, S.T.,Settembre, E.C.,Trask, S.D.,Greenberg, H.B.,Harrison, S.C.,Dormitzer, P.R. (登録日: 2008-12-22, 公開日: 2009-06-23, 最終更新日: 2023-09-06)

• 主引用文献: Aoki, S.T.,Settembre, E.C.,Trask, S.D.,Greenberg, H.B.,Harrison, S.C.,Dormitzer, P.R.; Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.; Science, 324:1444-1447, 2009; PubMed: 19520960; DOI: 10.1126/science.1170481

実験手法

X-RAY DIFFRACTION (3.4 Å)