3FM7

Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain

3FM7 の概要

• エントリーDOI: 10.2210/pdb3fm7/pdb
• 分子名称: Dynein light chain Tctex-type, Dynein intermediate chain, cytosolic, Dynein light chain 1, cytoplasmic (3 entities in total)
• 機能のキーワード: cytoplasmic dynein, light chain tctex-1, tctex, light chain 8, lc8, intermediate chain, ic, dynein cargo attachment complex, dynein light chain, quaternary structure, dynein, microtubule, motor protein, lysosome, membrane, nucleus, wd repeat, contractile protein
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton (Probable): Q94524; Cytoplasm, cytoskeleton. Isoform 2c: Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2a: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2b: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side: Q24246; Cytoplasm, cytoskeleton: Q24117
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 51868.55

構造登録者

Hall, J.D.,Karplus, P.A.,Barbar, E.J. (登録日: 2008-12-19, 公開日: 2009-09-15, 最終更新日: 2023-09-06)

• 主引用文献: Hall, J.,Karplus, P.A.,Barbar, E.; Multivalency in the assembly of intrinsically disordered Dynein intermediate chain.; J.Biol.Chem., 284:33115-33121, 2009; PubMed: 19759397; DOI: 10.1074/jbc.M109.048587

実験手法

X-RAY DIFFRACTION (3.5 Å)