3FHX

Crystal structure of D235A mutant of human pyridoxal kinase

Summary for 3FHX

• Entry DOI: 10.2210/pdb3fhx/pdb
• Related: 3FHY
• Descriptor: Pyridoxal kinase, MAGNESIUM ION, SODIUM ION, ... (9 entities in total)
• Functional Keywords: beta sheet with alpha helix, atp complex, metal ion, transferase, atp-binding, kinase, metal-binding, nucleotide-binding
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O00764
• Total number of polymer chains: 2
• Total formula weight: 73418.31

Authors

Safo, M.K.,Gandhi, A.K.,Musayev, F.N.,Ghatge, M.,Di Salvo, M.L.,Schirch, V. (deposition date: 2008-12-10, release date: 2008-12-23, Last modification date: 2023-09-06)

• Primary citation: Gandhi, A.K.,Ghatge, M.S.,Musayev, F.N.,Sease, A.,Aboagye, S.O.,di Salvo, M.L.,Schirch, V.,Safo, M.K.; Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase.; Biochem.Biophys.Res.Commun., 381:12-15, 2009; PubMed: 19351586; DOI: 10.1016/j.bbrc.2009.01.170

Experimental method

X-RAY DIFFRACTION (2.5 Å)