3FHJ

Independent saturation of three TrpRS subsites generates a partially-assembled state similar to those observed in molecular simulations

3FHJ の概要

• エントリーDOI: 10.2210/pdb3fhj/pdb
• 関連するPDBエントリー: 1D2R 1I6K 1I6L 1I6M 1M83 1MAU 1MB2 2OV4 3FI0
• 分子名称: Tryptophanyl-tRNA synthetase, TRYPTOPHAN, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: ligand-dependent domain rearrangement, mechanistic pathway, molecular simulations, aminoacyl-trna synthetase, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis, translation
• 由来する生物種: Bacillus stearothermophilus
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 227232.53

構造登録者

Laowanapiban, P.,Kapustina, M.,Vonrhein, C.,Delarue, M.,Koehl, P.,Carter Jr., C.W. (登録日: 2008-12-09, 公開日: 2009-02-03, 最終更新日: 2023-09-06)

• 主引用文献: Laowanapiban, P.,Kapustina, M.,Vonrhein, C.,Delarue, M.,Koehl, P.,Carter, C.W.; Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.; Proc.Natl.Acad.Sci.Usa, 106:1790-1795, 2009; PubMed: 19174517; DOI: 10.1073/pnas.0812752106

実験手法

X-RAY DIFFRACTION (2.65 Å)