3FGS

Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin

3FGS の概要

• エントリーDOI: 10.2210/pdb3fgs/pdb
• 関連するPDBエントリー: 1a8e 2O84
• 分子名称: Serotransferrin, CARBONATE ION, FE (III) ION, ... (4 entities in total)
• 機能のキーワード: human transferrin, iron binding protein, dilysine pair, disease mutation, glycoprotein, ion transport, iron, iron transport, metal-binding, methylation, phosphoprotein, polymorphism, secreted, transport, metal transport
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P02787
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37431.20

構造登録者

Halbrooks, P.J.,Mason, A.B.,Everse, S.J. (登録日: 2008-12-08, 公開日: 2009-05-19, 最終更新日: 2021-10-20)

• 主引用文献: Mason, A.B.,Halbrooks, P.J.,James, N.G.,Byrne, S.L.,Grady, J.K.,Chasteen, N.D.,Bobst, C.E.,Kaltashov, I.A.,Smith, V.C.,Macgillivray, R.T.,Everse, S.J.; Structural and Functional Consequences of the Substitution of Glycine 65 with Arginine in the N-Lobe of Human Transferrin.; Biochemistry, 48:1945-1953, 2009; PubMed: 19219998; DOI: 10.1021/bi802254x

実験手法

X-RAY DIFFRACTION (1.8 Å)