3FGO

Crystal Structure of the E2 magnesium fluoride complex of the (SR) Ca2+-ATPase with bound CPA and AMPPCP

Summary for 3FGO

Entry DOI	10.2210/pdb3fgo/pdb
Descriptor	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, TETRAFLUOROMAGNESATE(2-), ... (9 entities in total)
Functional Keywords	calcium pump, serca, nonhydrolyzable atp analog, p-type-atpase, phosphorylation, cyclopiazonic acid, cpa, alternative splicing, atp-binding, calcium, calcium transport, endoplasmic reticulum, hydrolase, ion transport, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, sarcoplasmic reticulum, transmembrane, transport
Biological source	Oryctolagus cuniculus (Rabbit)
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191
Total number of polymer chains	2
Total formula weight	221616.73
Authors	Laursen, M.,Bublitz, M.,Moncoq, K.,Olesen, C.,Moller, J.V.,Young, H.S.,Nissen, P.,Morth, J.P. (deposition date: 2008-12-08, release date: 2009-04-07, Last modification date: 2023-11-01)
Primary citation	Laursen, M.,Bublitz, M.,Moncoq, K.,Olesen, C.,Moeller, J.V.,Young, H.S.,Nissen, P.,Morth, J.P. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J.Biol.Chem., 2009 Cited by PubMed: 19289472 DOI: 10.1074/jbc.C900031200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation