3FGA

Structural Basis of PP2A and Sgo interaction

3FGA の概要

• エントリーDOI: 10.2210/pdb3fga/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000212
• 分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (7 entities in total)
• 機能のキーワード: pp2a, shugoshin, nucleus, phosphoprotein, hydrolase, iron, manganese, metal-binding, methylation, protein phosphatase, cell cycle, cell division, centromere, chromosome partition, mitosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm : Q76MZ3 P67775; Nucleus: Q13362 Q5FBB7
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 155274.26

構造登録者

Xu, Z.,Xu, W. (登録日: 2008-12-05, 公開日: 2009-09-22, 最終更新日: 2023-11-15)

• 主引用文献: Xu, Z.,Cetin, B.,Anger, M.,Cho, U.S.,Helmhart, W.,Nasmyth, K.,Xu, W.; Structure and function of the PP2A-shugoshin interaction; Mol.Cell, 35:426-441, 2009; PubMed: 19716788; DOI: 10.1016/j.molcel.2009.06.031

実験手法

X-RAY DIFFRACTION (2.7 Å)