3FF8

Structure of NK cell receptor KLRG1 bound to E-cadherin

Summary for 3FF8

Entry DOI	10.2210/pdb3ff8/pdb
Related	3FF7 3FF9
Descriptor	Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1, CALCIUM ION, ... (4 entities in total)
Functional Keywords	klrg1-cadherin complex, calcium, cell adhesion, cell junction, cell membrane, cleavage on pair of basic residues, disease mutation, glycoprotein, membrane, phosphoprotein, polymorphism, transmembrane, lectin, receptor, signal-anchor, cell adhesion-immune system complex, cell adhesion/immune system
Biological source	Homo sapiens (human) More
Cellular location	Cell junction : P12830 Cell membrane ; Single-pass type II membrane protein : O88713
Total number of polymer chains	4
Total formula weight	48901.88
Authors	Li, Y.,Mariuzza, R.A. (deposition date: 2008-12-02, release date: 2009-07-28, Last modification date: 2023-09-06)
Primary citation	Li, Y.,Hofmann, M.,Wang, Q.,Teng, L.,Chlewicki, L.K.,Pircher, H.,Mariuzza, R.A. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity, 31:35-46, 2009 Cited by PubMed: 19604491 DOI: 10.1016/j.immuni.2009.04.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation