3FEC

Crystal structure of human Glutamate Carboxypeptidase III (GCPIII/NAALADase II), pseudo-unliganded

3FEC の概要

• エントリーDOI: 10.2210/pdb3fec/pdb
• 関連するPDBエントリー: 3FED 3FEE 3FF3
• 分子名称: Glutamate carboxypeptidase III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... (10 entities in total)
• 機能のキーワード: metallopeptidase; bimetallic active site; n-glycosylation; calcium cation; chloride anion; zinc ions;, carboxypeptidase, dipeptidase, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, multifunctional enzyme, protease, signal-anchor, transmembrane
• 由来する生物種: Homo sapiens (man)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 81775.53

構造登録者

Barinka, C.,Lubkowski, J.,Hlouchova, K. (登録日: 2008-11-28, 公開日: 2009-08-25, 最終更新日: 2023-09-06)

• 主引用文献: Hlouchova, K.,Barinka, C.,Konvalinka, J.,Lubkowski, J.; Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III; Febs J., 276:4448-4462, 2009; PubMed: 19678840; DOI: 10.1111/j.1742-4658.2009.07152.x

実験手法

X-RAY DIFFRACTION (1.49 Å)