3FE2

Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP

3FE2 の概要

• エントリーDOI: 10.2210/pdb3fe2/pdb
• 分子名称: Probable ATP-dependent RNA helicase DDX5, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: rna helicase, dead, adp, atp-binding, hydrolase, nucleotide-binding, rna-binding, helicase, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, spliceosome, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus, nucleolus: P17844
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55720.88

構造登録者

Karlberg, T.,Siponen, M.I.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (登録日: 2008-11-27, 公開日: 2008-12-16, 最終更新日: 2023-11-01)

• 主引用文献: Schutz, P.,Karlberg, T.,van den Berg, S.,Collins, R.,Lehtio, L.,Hogbom, M.,Holmberg-Schiavone, L.,Tempel, W.,Park, H.W.,Hammarstrom, M.,Moche, M.,Thorsell, A.G.,Schuler, H.; Comparative Structural Analysis of Human DEAD-Box RNA Helicases; Plos One, 5:e12791-e12791, 2010; PubMed: 20941364; DOI: 10.1371/journal.pone.0012791

実験手法

X-RAY DIFFRACTION (2.6 Å)