3F9C
Crystal structure of human plasma platelet activating factor acetylhydrolase covalently inhibited by diisopropylfluorophosphate
Summary for 3F9C
Entry DOI | 10.2210/pdb3f9c/pdb |
Related | 3D59 3D5E 3F96 3F97 3F98 |
Descriptor | Platelet-activating factor acetylhydrolase, DIISOPROPYL PHOSPHONATE (3 entities in total) |
Functional Keywords | plasma platelet-activating factor acetylhydrolase, secreted protein, alpha/beta-hydrolase-fold, ldl-bound; lipoprotein associated phospholipase a2, lp-pla2, group viia pla2, glycoprotein, hydrolase, lipid degradation, polymorphism, diisopropylfluorophosphate, dfp, disease mutation, secreted |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted, extracellular space: Q13093 |
Total number of polymer chains | 2 |
Total formula weight | 87321.04 |
Authors | Samanta, U.,Bahnson, B.J. (deposition date: 2008-11-13, release date: 2009-06-23, Last modification date: 2023-09-06) |
Primary citation | Samanta, U.,Kirby, S.D.,Srinivasan, P.,Cerasoli, D.M.,Bahnson, B.J. Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes. Biochem Pharmacol, 78:420-429, 2009 Cited by PubMed: 19394314DOI: 10.1016/j.bcp.2009.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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