3F75

Activated Toxoplasma gondii cathepsin L (TgCPL) in complex with its propeptide

3F75 の概要

• エントリーDOI: 10.2210/pdb3f75/pdb
• 分子名称: Cathepsin L Protease, Cathepsin L Propeptide, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: medical structural genomics of pathogenic protozoa, msgpp, cysteine protease, parasite, protozoa, hydrolase, thiol protease
• 由来する生物種: Toxoplasma gondii; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37435.75

構造登録者

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (登録日: 2008-11-07, 公開日: 2008-11-25, 最終更新日: 2023-09-06)

• 主引用文献: Larson, E.T.,Parussini, F.,Huynh, M.H.,Giebel, J.D.,Kelley, A.M.,Zhang, L.,Bogyo, M.,Merritt, E.A.,Carruthers, V.B.; Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl.; J.Biol.Chem., 284:26839-26850, 2009; PubMed: 19596863; DOI: 10.1074/jbc.M109.003780

実験手法

X-RAY DIFFRACTION (1.99 Å)