3F2O
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide
Summary for 3F2O
Entry DOI | 10.2210/pdb3f2o/pdb |
Descriptor | SPRY domain-containing SOCS box protein 1, 20-mer peptide from ATP-dependent RNA helicase vasa (3 entities in total) |
Functional Keywords | apoptosis, nucleus, transcription regulation, sgc, structural genomics consortium, phosphoprotein, ubl conjugation pathway, atp-binding, developmental protein, differentiation, helicase, hydrolase, nucleotide-binding, oogenesis, apoptosis-hydrolase complex, apoptosis/hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm (Probable): Q96BD6 Cytoplasm: P09052 |
Total number of polymer chains | 4 |
Total formula weight | 58057.24 |
Authors | Filippakopoulos, P.,Sharpe, T.,Keates, T.,Murray, J.W.,Savitsky, P.,Roos, A.,Pike, A.C.W.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2008-10-30, release date: 2008-12-09, Last modification date: 2023-11-01) |
Primary citation | Filippakopoulos, P.,Low, A.,Sharpe, T.D.,Uppenberg, J.,Yao, S.,Kuang, Z.,Savitsky, P.,Lewis, R.S.,Nicholson, S.E.,Norton, R.S.,Bullock, A.N. Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. J.Mol.Biol., 401:389-402, 2010 Cited by PubMed: 20561531DOI: 10.1016/j.jmb.2010.06.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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