3F2O
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide
3F2O の概要
エントリーDOI | 10.2210/pdb3f2o/pdb |
分子名称 | SPRY domain-containing SOCS box protein 1, 20-mer peptide from ATP-dependent RNA helicase vasa (3 entities in total) |
機能のキーワード | apoptosis, nucleus, transcription regulation, sgc, structural genomics consortium, phosphoprotein, ubl conjugation pathway, atp-binding, developmental protein, differentiation, helicase, hydrolase, nucleotide-binding, oogenesis, apoptosis-hydrolase complex, apoptosis/hydrolase |
由来する生物種 | Homo sapiens (Human) 詳細 |
細胞内の位置 | Cytoplasm (Probable): Q96BD6 Cytoplasm: P09052 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 58057.24 |
構造登録者 | Filippakopoulos, P.,Sharpe, T.,Keates, T.,Murray, J.W.,Savitsky, P.,Roos, A.,Pike, A.C.W.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (登録日: 2008-10-30, 公開日: 2008-12-09, 最終更新日: 2023-11-01) |
主引用文献 | Filippakopoulos, P.,Low, A.,Sharpe, T.D.,Uppenberg, J.,Yao, S.,Kuang, Z.,Savitsky, P.,Lewis, R.S.,Nicholson, S.E.,Norton, R.S.,Bullock, A.N. Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. J.Mol.Biol., 401:389-402, 2010 Cited by PubMed: 20561531DOI: 10.1016/j.jmb.2010.06.017 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.05 Å) |
構造検証レポート
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