3EYK

Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion

Summary for 3EYK

Related3EYJ 3EYM
DescriptorHemagglutinin HA1 chain, Hemagglutinin HA2 chain, 2-tert-butylbenzene-1,4-diol, ... (4 entities in total)
Functional Keywordsinfluenza, hemagglutinin, inhibitor, envelope protein, fusion protein, glycoprotein, lipoprotein, membrane, palmitate, transmembrane, virion, viral protein
Biological sourceInfluenza A virus
Cellular locationVirion membrane; Single-pass type I membrane protein (Potential) P26137 P26137
Total number of polymer chains2
Total molecular weight55368.85
Authors
Russell, R.J.,Kerry, P.S.,Stevens, D.J.,Steinhauer, D.A.,Martin, S.R.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2008-10-21, release date: 2009-01-13, Last modification date: 2011-07-13)
Primary citation
Russell, R.J.,Kerry, P.S.,Stevens, D.J.,Steinhauer, D.A.,Martin, S.R.,Gamblin, S.J.,Skehel, J.J.
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105:17736-17741, 2008
PubMed: 19004788 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0807142105
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.259100.4%0.7%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution