3EUU
Crystal structure of the FGFR2 D2 domain
Summary for 3EUU
Entry DOI | 10.2210/pdb3euu/pdb |
Related | 3CAF |
Descriptor | Fibroblast growth factor receptor 2 (2 entities in total) |
Functional Keywords | ig-like, alternative splicing, atp-binding, cell membrane, craniosynostosis, disease mutation, ectodermal dysplasia, glycoprotein, heparin-binding, immunoglobulin domain, kinase, lacrimo-auriculo-dento-digital syndrome, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802 |
Total number of polymer chains | 2 |
Total formula weight | 23216.52 |
Authors | Sakon, J.,Guo, F.,Dakshinamurthy, R.,Kathir, K.M.,Thallapuranam, S.K.K. (deposition date: 2008-10-10, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Guo, F.,Dakshinamurthy, R.,Kathir, K.M.,Thallapuranam, S.K.K.,Sakon, J. Crystal structure of the D2 domain of hFGFR2 To be Published, |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
Download full validation report