3EU0
Crystal structure of the S-nitrosylated Cys215 of PTP1B
Summary for 3EU0
Entry DOI | 10.2210/pdb3eu0/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1 (2 entities in total) |
Functional Keywords | s-nitrosylated protein, hydrolase, acetylation, endoplasmic reticulum, membrane, oxidation, phosphoprotein, polymorphism, protein phosphatase |
Biological source | Homo sapiens (Human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031 |
Total number of polymer chains | 1 |
Total formula weight | 38223.51 |
Authors | Chu, H.M.,Wang, A.H.J.,Chen, Y.Y.,Pan, K.T.,Wang, D.L.,Khoo, K.H.,Meng, T.C. (deposition date: 2008-10-09, release date: 2008-11-11, Last modification date: 2023-11-01) |
Primary citation | Chen, Y.Y.,Chu, H.M.,Pan, K.T.,Teng, C.H.,Wang, D.L.,Wang, A.H.,Khoo, K.H.,Meng, T.C. Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation J.Biol.Chem., 283:35265-35272, 2008 Cited by PubMed: 18840608DOI: 10.1074/jbc.M805287200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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