3ETB

Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4

Summary for 3ETB

Entry DOI	10.2210/pdb3etb/pdb
Related	3ESU 3ESV 3ET9
Descriptor	Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker, Anthrax Protective Antigen (2 entities in total)
Functional Keywords	single-chain fv, monoclonal antibody, immunoglobulin, toxin, antibody-antigen complex, immune system-toxin complex, immune system/toxin
Biological source	Mus musculus (mouse) More
Cellular location	Secreted, extracellular space: P13423
Total number of polymer chains	8
Total formula weight	173464.69
Authors	Monzingo, A.F.,Leysath, C.E.,Barnett, J.,Iverson, B.L.,Georgiou, G.,Robertus, J.D. (deposition date: 2008-10-07, release date: 2009-04-28, Last modification date: 2023-09-06)
Primary citation	Leysath, C.E.,Monzingo, A.F.,Maynard, J.A.,Barnett, J.,Georgiou, G.,Iverson, B.L.,Robertus, J.D. Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. J.Mol.Biol., 387:680-693, 2009 Cited by PubMed: 19361425 DOI: 10.1016/j.jmb.2009.02.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation