3ESK
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
Summary for 3ESK
Entry DOI | 10.2210/pdb3esk/pdb |
Related | 1ELR 1ELW |
Descriptor | Stress-induced-phosphoprotein 1, Heat shock cognate 71 kDa protein, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | tpr2a, hsp90, hsc70, tetratricopeptide repeat, nucleus, tpr repeat, chaperone, stress response |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm (By similarity): P31948 Cytoplasm: P11142 |
Total number of polymer chains | 2 |
Total formula weight | 16474.09 |
Authors | Kajander, T.,Regan, L. (deposition date: 2008-10-06, release date: 2009-07-07, Last modification date: 2023-09-06) |
Primary citation | Kajander, T.,Sachs, J.N.,Goldman, A.,Regan, L. Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. J.Biol.Chem., 284:25364-25374, 2009 Cited by PubMed: 19586912DOI: 10.1074/jbc.M109.033894 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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