3ENM

The structure of the MAP2K MEK6 reveals an autoinhibitory dimer

3ENM の概要

• エントリーDOI: 10.2210/pdb3enm/pdb
• 分子名称: Dual specificity mitogen-activated protein kinase kinase 6, SULFATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: mek6, autoinhibited dimer, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 147194.66

構造登録者

Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.,Lee, S.-J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J. (登録日: 2008-09-25, 公開日: 2009-03-03, 最終更新日: 2021-10-20)

• 主引用文献: Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.E.,Lee, S.J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J.; The structure of the MAP2K MEK6 reveals an autoinhibitory dimer; Structure, 17:96-104, 2009; PubMed: 19141286; DOI: 10.1016/j.str.2008.11.007

実験手法

X-RAY DIFFRACTION (2.35 Å)