3EIQ

Crystal structure of Pdcd4-eIF4A

3EIQ の概要

• エントリーDOI: 10.2210/pdb3eiq/pdb
• 分子名称: Eukaryotic initiation factor 4A-I, Programmed cell death protein 4 (2 entities in total)
• 機能のキーワード: pdcd4, anti-oncogene, apoptosis, cell cycle, nucleus, phosphoprotein, rna-binding, atp-binding, helicase, hydrolase, initiation factor, nucleotide-binding, protein biosynthesis, antitumor protein, translation, hydrolase-antitumor protein complex, hydrolase/antitumor protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P60842
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 133827.52

構造登録者

Loh, P.G.,Cheng, Z.,Song, H. (登録日: 2008-09-17, 公開日: 2009-02-24, 最終更新日: 2023-11-01)

• 主引用文献: Loh, P.G.,Yang, H.S.,Walsh, M.A.,Wang, Q.,Wang, X.,Cheng, Z.,Liu, D.,Song, H.; Structural basis for translational inhibition by the tumour suppressor Pdcd4; Embo J., 28:274-285, 2009; PubMed: 19153607; DOI: 10.1038/emboj.2008.278

実験手法

X-RAY DIFFRACTION (3.5 Å)