3EI1

Structure of hsDDB1-drDDB2 bound to a 14 bp 6-4 photoproduct containing DNA-duplex

Summary for 3EI1

• Entry DOI: 10.2210/pdb3ei1/pdb
• Related: 3EI2 3EI3 3EI4
• Descriptor: DNA damage-binding protein 1, DNA damage-binding protein 2, 5'-D(*DAP*DCP*DGP*DCP*DGP*DAP*(64T)P*(5PY)P*DGP*DCP*DGP*DCP*DCP*DC)-3', ... (6 entities in total)
• Functional Keywords: uv-damage, ddb, nucleotide excision repair, xeroderma pigmentosum, alternative splicing, disease mutation, dna damage, dna repair, dna-binding, nucleus, phosphoprotein, polymorphism, wd repeat, ubl conjugation pathway, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: Q16531; Nucleus (By similarity): Q2YDS1
• Total number of polymer chains: 4
• Total formula weight: 181572.81

Authors

Scrima, A.,Thoma, N.H. (deposition date: 2008-09-15, release date: 2009-01-20, Last modification date: 2024-03-20)

• Primary citation: Scrima, A.,Konickova, R.,Czyzewski, B.K.,Kawasaki, Y.,Jeffrey, P.D.,Groisman, R.,Nakatani, Y.,Iwai, S.,Pavletich, N.P.,Thoma, N.H.; Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.; Cell(Cambridge,Mass.), 135:1213-1223, 2008; PubMed: 19109893; DOI: 10.1016/j.cell.2008.10.045

Experimental method

X-RAY DIFFRACTION (2.8 Å)