3EI1

Structure of hsDDB1-drDDB2 bound to a 14 bp 6-4 photoproduct containing DNA-duplex

3EI1 の概要

• エントリーDOI: 10.2210/pdb3ei1/pdb
• 関連するPDBエントリー: 3EI2 3EI3 3EI4
• 分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, 5'-D(*DAP*DCP*DGP*DCP*DGP*DAP*(64T)P*(5PY)P*DGP*DCP*DGP*DCP*DCP*DC)-3', ... (6 entities in total)
• 機能のキーワード: uv-damage, ddb, nucleotide excision repair, xeroderma pigmentosum, alternative splicing, disease mutation, dna damage, dna repair, dna-binding, nucleus, phosphoprotein, polymorphism, wd repeat, ubl conjugation pathway, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm: Q16531; Nucleus (By similarity): Q2YDS1
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 181572.81

構造登録者

Scrima, A.,Thoma, N.H. (登録日: 2008-09-15, 公開日: 2009-01-20, 最終更新日: 2024-03-20)

• 主引用文献: Scrima, A.,Konickova, R.,Czyzewski, B.K.,Kawasaki, Y.,Jeffrey, P.D.,Groisman, R.,Nakatani, Y.,Iwai, S.,Pavletich, N.P.,Thoma, N.H.; Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.; Cell(Cambridge,Mass.), 135:1213-1223, 2008; PubMed: 19109893; DOI: 10.1016/j.cell.2008.10.045

実験手法

X-RAY DIFFRACTION (2.8 Å)