3ED0

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin

3ED0 の概要

• エントリーDOI: 10.2210/pdb3ed0/pdb
• 関連するPDBエントリー: 2GLL
• 分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: fabz complex, emodin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase
• 由来する生物種: Helicobacter pylori
• 細胞内の位置: Cytoplasm (By similarity): Q5G940
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 110830.97

構造登録者

Zhang, L.,Zhang, H.,Liu, W.,Guo, Y.,Shen, X.,Jiang, H. (登録日: 2008-09-02, 公開日: 2009-07-21, 最終更新日: 2023-11-01)

• 主引用文献: Chen, J.,Zhang, L.,Zhang, Y.,Zhang, H.,Du, J.,Ding, J.,Guo, Y.,Jiang, H.,Shen, X.; Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization; BMC MICROBIOL., 9:91-91, 2009; PubMed: 19433000; DOI: 10.1186/1471-2180-9-91

実験手法

X-RAY DIFFRACTION (2.3 Å)