3EAJ

Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with two molecules in one asymmetric unit

3EAJ の概要

• エントリーDOI: 10.2210/pdb3eaj/pdb
• 関連するPDBエントリー: 3E91 3EA7 3EA8 3EA9
• 分子名称: 3C-like proteinase (2 entities in total)
• 機能のキーワード: sars coronavirus main protease mutant extra helical domain, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• 由来する生物種: SARS coronavirus (SARS-CoV)
• 細胞内の位置: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67424.88

構造登録者

Shi, J.H.,Jayaraman, S.,Song, J.X. (登録日: 2008-08-26, 公開日: 2009-09-01, 最終更新日: 2023-11-01)

• 主引用文献: Shi, J.H.,Jayaraman, S.,Song, J.X.; crystal structure of SARS-CoV Mpro mutant with two molecules one ASU; To be Published,

実験手法

X-RAY DIFFRACTION (2.7 Å)