3EAB
Crystal structure of Spastin MIT in complex with ESCRT III
Summary for 3EAB
Entry DOI | 10.2210/pdb3eab/pdb |
Descriptor | Spastin, CHMP1b (2 entities in total) |
Functional Keywords | spastin, chmp, mit, escrt, alternative splicing, atp-binding, cytoplasm, disease mutation, hereditary spastic paraplegia, nucleotide-binding, nucleus, polymorphism, cell cycle |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass membrane protein (Potential): Q9UBP0 |
Total number of polymer chains | 12 |
Total formula weight | 94415.32 |
Authors | Yang, D.,Rimanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H. (deposition date: 2008-08-25, release date: 2008-11-11, Last modification date: 2024-02-21) |
Primary citation | Yang, D.,Rismanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H. Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. Nat.Struct.Mol.Biol., 15:1278-1286, 2008 Cited by PubMed: 18997780DOI: 10.1038/nsmb.1512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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