3EAB

Crystal structure of Spastin MIT in complex with ESCRT III

3EAB の概要

• エントリーDOI: 10.2210/pdb3eab/pdb
• 分子名称: Spastin, CHMP1b (2 entities in total)
• 機能のキーワード: spastin, chmp, mit, escrt, alternative splicing, atp-binding, cytoplasm, disease mutation, hereditary spastic paraplegia, nucleotide-binding, nucleus, polymorphism, cell cycle
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Membrane; Single-pass membrane protein (Potential): Q9UBP0
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 94415.32

構造登録者

Yang, D.,Rimanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H. (登録日: 2008-08-25, 公開日: 2008-11-11, 最終更新日: 2024-02-21)

• 主引用文献: Yang, D.,Rismanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H.; Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.; Nat.Struct.Mol.Biol., 15:1278-1286, 2008; PubMed: 18997780; DOI: 10.1038/nsmb.1512

実験手法

X-RAY DIFFRACTION (2.5 Å)