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3EA5

Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics

Summary for 3EA5
Entry DOI10.2210/pdb3ea5/pdb
DescriptorGTP-binding nuclear protein Ran, Importin subunit beta-1, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordskaryopherin, importin, ran, gtp-binding, host-virus interaction, nucleotide-binding, nucleus, phosphoprotein, protein transport, transport, transport protein
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P62826
Cytoplasm (By similarity): Q06142
Total number of polymer chains4
Total formula weight239678.54
Authors
Forwood, J.K.,Lonhienne, J.K.,Guncar, G.,Stewart, M.,Marfori, M.,Kobe, B. (deposition date: 2008-08-24, release date: 2008-10-21, Last modification date: 2024-02-21)
Primary citationForwood, J.K.,Lonhienne, T.G.,Marfori, M.,Robin, G.,Meng, W.,Guncar, G.,Liu, S.M.,Stewart, M.,Carroll, B.J.,Kobe, B.
Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383:772-782, 2008
Cited by
PubMed: 18708071
DOI: 10.1016/j.jmb.2008.07.090
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

数据于2024-03-27公开中

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