3E7V

Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand

3E7V の概要

• エントリーDOI: 10.2210/pdb3e7v/pdb
• 分子名称: Serine/threonine-protein kinase haspin, 3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine, NICKEL (II) ION, ... (5 entities in total)
• 機能のキーワード: haspin, germ cell associated 2 (haspin), haploid germ cell specific nuclear protein kinase, sgc, structural genomics consortium, atp-binding, cell cycle, chromatin regulator, kinase, magnesium, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : Q8TF76
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41540.44

構造登録者

Filippakopoulos, P.,Eswaran, J.,Keates, T.,Burgess-Brown, N.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Wickstroem, M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2008-08-19, 公開日: 2008-10-14, 最終更新日: 2023-08-30)

• 主引用文献: Filippakopoulos, P.,Eswaran, J.,Keates, T.,Burgess-Brown, N.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Wickstroem, M.,Bountra, C.,Knapp, S.; Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand; To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)