3E4C
Procaspase-1 zymogen domain crystal structure
Summary for 3E4C
Entry DOI | 10.2210/pdb3e4c/pdb |
Related | 1RWX |
Descriptor | Caspase-1, MAGNESIUM ION (3 entities in total) |
Functional Keywords | zymogen, caspase-1, inflammasome, ice, caspase, il-1b, procaspase-1, procaspase, innate immunity, apoptosis, hydrolase, protease, thiol protease |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 67619.11 |
Authors | Elliott, J.M.,Rouge, L.,Wiesmann, C.,Scheer, J.M. (deposition date: 2008-08-11, release date: 2008-12-30, Last modification date: 2023-08-30) |
Primary citation | Elliott, J.M.,Rouge, L.,Wiesmann, C.,Scheer, J.M. Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation J.Biol.Chem., 284:6546-6553, 2009 Cited by PubMed: 19117953DOI: 10.1074/jbc.M806121200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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