3E2P

Catalytic subunit of M. Jannaschii aspartate transcarbamoylase in an orthorhombic crystal form

3E2P の概要

• エントリーDOI: 10.2210/pdb3e2p/pdb
• 分子名称: Aspartate carbamoyltransferase, SULFATE ION (3 entities in total)
• 機能のキーワード: aspartate transcarbamoylase, atcase, pyrimidine biosynthesis, thermostability, methanococcus jannaschii, transferase
• 由来する生物種: Methanocaldococcus jannaschii (Methanococcus jannaschii)
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 422911.70

構造登録者

Vitali, J.,Colaneri, M.J. (登録日: 2008-08-06, 公開日: 2009-03-10, 最終更新日: 2023-08-30)

主引用文献

Vitali, J.,Colaneri, M.J.
Structure of the catalytic trimer of Methanococcus jannaschii aspartate transcarbamoylase in an orthorhombic crystal form.
Acta Crystallogr.,Sect.F, 64:776-780, 2008

PubMed Abstract: Crystals of the catalytic subunit of Methanococcus jannaschii aspartate transcarbamoylase in an orthorhombic crystal form contain four crystallographically independent trimers which associate in pairs to form stable staggered complexes that are similar to each other and to a previously determined monoclinic C2 form. Each subunit has a sulfate in the central channel. The catalytic subunits in these complexes show flexibility, with the elbow angles of the monomers differing by up to 7.4 degrees between crystal forms. Moreover, there is also flexibility in the relative orientation of the trimers around their threefold axis in the complexes, with a difference of 4 degrees between crystal forms.

PubMed: 18765902
DOI: 10.1107/S1744309108025359

実験手法

X-RAY DIFFRACTION (3 Å)