3E1U

The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain

3E1U の概要

• エントリーDOI: 10.2210/pdb3e1u/pdb
• 分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION (3 entities in total)
• 機能のキーワード: five beta-strands surrounded by six alpha-helices, alternative splicing, antiviral defense, cytoplasm, host-virus interaction, hydrolase, metal-binding, nucleus, polymorphism, ubl conjugation, zinc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q9HC16
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22153.40

構造登録者

Holden, L.,Prochnow, C.,Chang, Y.P.,Bransteitter, R.,Chelico, L.,Sen, U.,Stevens, R.C.,Goodman, R.F.,Chen, X.S. (登録日: 2008-08-04, 公開日: 2008-10-07, 最終更新日: 2024-02-21)

• 主引用文献: Holden, L.G.,Prochnow, C.,Chang, Y.P.,Bransteitter, R.,Chelico, L.,Sen, U.,Stevens, R.C.,Goodman, M.F.,Chen, X.S.; Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.; Nature, 456:121-124, 2008; PubMed: 18849968; DOI: 10.1038/nature07357

実験手法

X-RAY DIFFRACTION (2.3 Å)