3E04
Crystal structure of human fumarate hydratase
Summary for 3E04
Entry DOI | 10.2210/pdb3e04/pdb |
Descriptor | Fumarate hydratase, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | fumarase, tca cycle, structural genomics consortium, alternative initiation, anti-oncogene, cell cycle, disease mutation, lyase, mitochondrion, transit peptide, tricarboxylic acid cycle, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P07954 |
Total number of polymer chains | 4 |
Total formula weight | 212028.24 |
Authors | Kavanagh, K.L.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2008-07-30, release date: 2008-08-12, Last modification date: 2023-08-30) |
Primary citation | Kavanagh, K.L.,Picaud, S.,Pilka, E.S.,Yue, W.W.,Roos, A.K.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Wikstrom, M.,Edwards, A.M.,Bountra, C.,Oppermann, U.,Structural Genomics Consortium (SGC) Crystal structure of human fumarate hydratase TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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