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3E04

Crystal structure of human fumarate hydratase

Summary for 3E04
Entry DOI10.2210/pdb3e04/pdb
DescriptorFumarate hydratase, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordsfumarase, tca cycle, structural genomics consortium, alternative initiation, anti-oncogene, cell cycle, disease mutation, lyase, mitochondrion, transit peptide, tricarboxylic acid cycle, sgc
Biological sourceHomo sapiens (human)
Cellular locationIsoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P07954
Total number of polymer chains4
Total formula weight212028.24
Authors
Kavanagh, K.L.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2008-07-30, release date: 2008-08-12, Last modification date: 2023-08-30)
Primary citationKavanagh, K.L.,Picaud, S.,Pilka, E.S.,Yue, W.W.,Roos, A.K.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Wikstrom, M.,Edwards, A.M.,Bountra, C.,Oppermann, U.,Structural Genomics Consortium (SGC)
Crystal structure of human fumarate hydratase
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

217705

数据于2024-03-27公开中

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