3DZU

Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide

Summary for 3DZU

• Entry DOI: 10.2210/pdb3dzu/pdb
• Related: 3DZY 3E00
• Descriptor: Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ... (8 entities in total)
• Functional Keywords: dna-binding, host-virus interaction, metal-binding, nucleus, receptor, transcription, transcription regulation, zinc-finger, activator, diabetes mellitus, disease mutation, obesity, phosphoprotein, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P19793 P37231 Q15596
• Total number of polymer chains: 6
• Total formula weight: 116168.56

Authors

Chandra, V.,Huang, P.,Hamuro, Y.,Raghuram, S.,Wang, Y.,Burris, T.P.,Rastinejad, F. (deposition date: 2008-07-30, release date: 2008-10-28, Last modification date: 2024-02-21)

• Primary citation: Chandra, V.,Huang, P.,Hamuro, Y.,Raghuram, S.,Wang, Y.,Burris, T.P.,Rastinejad, F.; Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.; Nature, 456:350-356, 2008; PubMed: 19043829; DOI: 10.1038/nature07413

Experimental method

X-RAY DIFFRACTION (3.2 Å)