3DZG

Crystal structure of human CD38 extracellular domain, ara-F-ribose-5'-phosphate/nicotinamide complex

3DZG の概要

関連するPDBエントリー3DZF 3DZH 3DZI 3DZJ 3DZK
分子名称ADP-ribosyl cyclase 1, 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose, NICOTINAMIDE, ... (4 entities in total)
機能のキーワードcovalent intermediate complex, nicotinamide complex, beta sheets, alpha bundle, diabetes mellitus, glycoprotein, hydrolase, membrane, nad, receptor, signal-anchor, transmembrane
由来する生物種Homo sapiens
細胞内の位置Membrane; Single-pass type II membrane protein P28907
ポリマー鎖数2
分子量合計61469.24
構造登録者
Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. (登録日: 2008-07-29, 公開日: 2008-11-04, 最終更新日: 2016-06-08)
主引用文献
Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q.
Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15:1068-1078, 2008
PubMed: 18940667 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.chembiol.2008.08.007
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.65 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliers0.28781.0%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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