3DWQ

Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc

Summary for 3DWQ

Entry DOI	10.2210/pdb3dwq/pdb
Related	3dwa 3dwp
Descriptor	Subtilase cytotoxin, subunit B, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-PROPANOL, ... (6 entities in total)
Functional Keywords	toxin
Biological source	Escherichia coli
Total number of polymer chains	5
Total formula weight	74530.25
Authors	Byres, E.,Paton, A.W.,Paton, J.C.,Lofling, J.C.,Smith, D.F.,Wilce, M.C.J.,Talbot, U.M.,Chong, D.C.,Yu, H.,Huang, S.,Chen, X.,Varki, N.M.,Varki, A.,Rossjohn, J.,Beddoe, T. (deposition date: 2008-07-22, release date: 2008-11-04, Last modification date: 2020-07-29)
Primary citation	Byres, E.,Paton, A.W.,Paton, J.C.,Lofling, J.C.,Smith, D.F.,Wilce, M.C.J.,Talbot, U.M.,Chong, D.C.,Yu, H.,Huang, S.,Chen, X.,Varki, N.M.,Varki, A.,Rossjohn, J.,Beddoe, T. Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456:648-652, 2008 Cited by PubMed: 18971931 DOI: 10.1038/nature07428 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation